This was Percy Sledge’s 3rd single from Atlantic, following his mega-hit “When A Man Loves a Woman” and “Warm and Tender Love”. In December, 1966 the song reached #7 in the US R&B charts and #12 in Canada. As always, Sledge sings with enormous passion and you can feel his anguish and loss with every word.
Percy Sledge – It Tears Me Up (Atlantic)

He must have been something live.
For sure. I wish I could have seen him live along with James Brown circa 66-67.